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Article

Arterial injury promotes medial chondrogenesis in Sm22 knockout mice.

Cardiovascular research - 1 Apr 2011

Shen Jianbin, Yang Maozhou, Jiang Hong, Ju Donghong, Zheng Jian-Pu, Xu Zhonghui, Liao Tang-Dong, Li Li

Abstract excerpt

AIMS: Expression of SM22 (also known as SM22alpha and transgelin), a vascular smooth muscle cells (VSMCs) marker, is down-regulated in arterial diseases involving medial osteochondrogenesis. We investigated the effect of SM22 deficiency in a mouse artery injury model to determine the role of SM22 in arterial chondrogenesis. METHODS AND RESULTS: Sm22 knockout (Sm22(-/-)) mice developed prominent medial...

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Source

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Identifiers

PMID: 21183509
DOI: 10.1093/cvr/cvq378
PMCID: PMC3058734

Genes

SOX9
SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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