Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gremlin promotes vascular smooth muscle cell proliferation and migration.

Journal of molecular and cellular cardiology - 1 Feb 2008

Maciel Thiago T, Melo Rosilene S, Schor Nestor, Campos Alexandre H

Abstract excerpt

Recent reports highlight the importance of BMP in the vasculature. We investigated the expression pattern and role of the BMP antagonist gremlin in VSMC. We detected gremlin mRNA constitutive expression in adult and embryonic rat aortic VSMC, and in rat carotids. In vitro analysis demonstrated that angiotensin II, TGF-beta1 and PDGF induced significant changes in gremlin mRNA expression. Gremlin stable...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Morphogenetic Proteins
Share to Cyclin-Dependent Kinase Inhibitor p27

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Silencing

Share to Intercellular Signaling Peptides and Proteins

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Rats, Sprague-Dawley

Share to Tunica Intima

Source

Identifiers

PMID: 18086474
DOI: 10.1016/j.yjmcc.2007.10.021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gremlin promotes vascular smooth muscle cell proliferation and migration.PMID 18086474Read ↗

Overexpression of Gremlin-1 in Patients with Loeys-Dietz Syndrome: Implications on Pathophysiology and Early Disease DetectionSemantic proximity Read ↗

Vascular smooth muscle cell Smad4 gene is important for mouse vascular development.Semantic proximity Read ↗

Insights into the Role of Gremlin-1, a Bone Morphogenic Protein Antagonist, in Cancer Initiation and ProgressionSemantic proximity Read ↗

Transforming growth factor-betas and vascular disorders.Semantic proximity Read ↗

Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading.Semantic proximity Read ↗

Krüppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor beta 1 in the regulation of vascular smooth muscle cell phenotype.Semantic proximity Read ↗

miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.Semantic proximity Read ↗

Regulation of Vascular Smooth Muscle Cell Dysfunction Under Diabetic Conditions by miR-504.Semantic proximity Read ↗

Smad7 misexpression during embryonic angiogenesis causes vascular dilation and malformations independently of vascular smooth muscle cell function.Semantic proximity Read ↗

FBLN7 mediates vascular smooth muscle cell phenotype switching and vascular remodeling in hypertension.Semantic proximity Read ↗

Role of Gremlin in the LungSemantic proximity Read ↗

How do microRNAs affect vascular smooth muscle cell biology?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.