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Article

Genetic and epigenetic alterations of WWOX in the development of gastric cardia adenocarcinoma.

Environmental and molecular mutagenesis - 1 Mar 2013

Guo Wei, Dong Zhiming, Dong Yuran, Guo Yanli, Kuang Gang, Yang Zhibin

Abstract excerpt

WWOX is a tumor suppressor gene that maps to the common fragile site FRA16D and is involved in carcinogenesis and cancer progression in many different carcinomas. Reduced WWOX expression is associated with more aggressive phenotypes and poor patient outcomes in several cancers. The present study was conducted in order to elucidate more precisely the genetic and epigenetic alterations of WWOX that play a role in...

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Source

Identifiers

PMID: 23197378
DOI: 10.1002/em.21748

Genes

WWOX
GCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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