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Article

Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma.

Cancer research - 15 Apr 2002

Kuroki Tamotsu, Trapasso Francesco, Shiraishi Takeshi, Alder Hansjuerg, Mimori Koshi, Mori Masaki, Croce Carlo M

Abstract excerpt

The WWOX (WW domain containing oxidoreductase) gene was recently identified as a candidate tumor suppressor gene at 16q23.3-24.1, a chromosome region that spans the common fragile site FRA16D. To evaluate the potential role of the WWOX gene in esophageal squamous cell carcinomas, we examined 36 t...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Loss of Heterozygosity

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Source

Identifiers

PMID: 11956080

Genes

WWOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11956080-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma.PMID 11956080Read ↗

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Genetic and epigenetic alterations of WWOX in the development of gastric cardia adenocarcinoma.Semantic proximity Read ↗

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer.Semantic proximity Read ↗

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