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Article

Clinical risk factors and serotonin transporter gene variants associated with antidepressant-induced mania.

The Journal of clinical psychiatry - 1 Feb 2015

Frye Mark A, McElroy Susan L, Prieto Miguel L, Harper Kelly L, Walker Denise L, Kung Simon, Chauhan Mohit, Crow Scott, Sutor Bruce, Galardy Christine W, Veldic Marin, Palmer Brian A, Geske Jennifer R, Fuentes Manuel, Cuellar-Barboza Alfredo B, Seymour Lisa R, Mori Nicole, Biernacka Joanna M

Abstract excerpt

INTRODUCTION: Identifying clinical and genetic risk factors associated with antidepressant-induced mania (AIM) may improve individualized treatment strategies for bipolar depression. METHOD: From 2009 to 2012, bipolar depressed patients, confirmed by DSM-IV-TR-structured interview, were screened for AIM. An AIM+ case was defined as a manic/hypomanic episode within 60 days of starting or changing dose of...

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Identifiers

PMID: 25611077
DOI: 10.4088/JCP.14m09127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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