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Article

The role of serotonin transporter protein gene in antidepressant-induced mania in bipolar disorder: preliminary findings.

Archives of general psychiatry - 1 Jun 2001

Mundo E, Walker M, Cate T, Macciardi F, Kennedy J L

Abstract excerpt

BACKGROUND: The occurrence of mania during antidepressant treatment is a key issue in the clinical management of bipolar disorder (BP). The serotonin transporter (5-HTT) is the selective site of action of most proserotonergic compounds used to treat bipolar depression. The 5-HTT gene (SLC6A4) has 2 known polymorphisms. The aim of this study was to investigate the role of the SLC6A4 variants in the pathogenesis of...

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Source

Identifiers

PMID: 11386982
DOI: 10.1001/archpsyc.58.6.539

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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