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Article

Antidepressant-induced mania, rapid cycling and the serotonin transporter gene polymorphism.

The pharmacogenomics journal - 1 Jan 2003

Rousseva A, Henry C, van den Bulke D, Fournier G, Laplanche J-L, Leboyer M, Bellivier F, Aubry J-M, Baud P, Boucherie M, Buresi C, Ferrero F, Malafosse A

Abstract excerpt

The genes involved in the serotonin system are major candidates in association studies on affective disorders and responses to antidepressants. We studied a functional polymorphism of the serotonin transporter (5-HTT) gene (a 44 bp insertion/deletion in the 5-HTT-linked polymorphic region (5-HTTLPR)) and lifetime history of antidepressant-induced mania (AIM) in a population of 305 patients with bipolar affective...

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PMID: 12746735
DOI: 10.1038/sj.tpj.6500156

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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