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Article

The role of 5-HTTLPR polymorphism in antidepressant-associated mania in bipolar disorder.

Journal of affective disorders - 1 Jan 2009

Ferreira Alexandre de Aguiar, Neves Fernando Silva, da Rocha Felipe Filardi, Silva Gustavo Silveira E, Romano-Silva Marco Aurélio, Miranda Débora Marques, De Marco Luiz, Correa Humberto

Abstract excerpt

BACKGROUND: The occurrence of mania during antidepressant treatment is a key issue in the clinical management of bipolar disorder (BD). The serotonin transporter gene is a candidate to be associated with antidepressant-associated mania (AAM) in some patients. This gene has a polymorphism within the promoter region (5-HTTLPR) with two allelic forms, the long (L) and the short (S) variants. METHODS: We performed a...

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Identifiers

PMID: 18534687
DOI: 10.1016/j.jad.2008.04.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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