Article
Brain-derived neurotrophic factor (BDNF) gene not associated with antidepressant-induced mania.
Bipolar disorders - 1 Aug 2007
Zai Gwyneth, Mundo Emanuela, Strauss John, Wong Gregory W H, Kennedy James L
Abstract excerpt
BACKGROUND: Brain-derived neurotrophic factor (BDNF) plays an important role in the regulation of synaptic plasticity and neurotransmitter release across multiple neurotransmitter systems. Recent studies have suggested that BDNF plays a role in the pathogenesis of bipolar disorder (BPD). Moreover, increasing BDNF production might be one of the mechanisms involved in the alleviation of depression and aggravation...
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