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Article

Associations of the serotonin transporter promoter polymorphism (5-HTTLPR) with bipolar disorder and treatment response: A systematic review and meta-analysis.

Progress in neuro-psychopharmacology & biological psychiatry - 8 Mar 2019

Rao Shitao, Han Xinyu, Shi Mai, Siu Cynthia O, Waye Mary Miu Yee, Liu Guangming, Wing Yun Kwok

Abstract excerpt

BACKGROUND: Associations of the serotonin transporter promoter polymorphism (5-HTTLPR) with bipolar disorder (BPD) and treatment response in bipolar patients were not conclusive. This study not only assessed the association between the 5-HTTLPR and BPD with accumulating relevant studies, but also in the first time evaluated the effect of the 5-HTTLPR on both anti-depressive and anti-manic treatment responses in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Serotonin Plasma Membrane Transport Proteins

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Source

Identifiers

PMID: 30217771
DOI: 10.1016/j.pnpbp.2018.08.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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