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Article

Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated Genes in Seminomas.

European urology - 1 Jul 2015

Cutcutache Ioana, Suzuki Yuka, Tan Iain Beehuat, Ramgopal Subhashini, Zhang Shenli, Ramnarayanan Kalpana, Gan Anna, Lee Heng Hong, Tay Su Ting, Ooi Aikseng, Ong Choon Kiat, Bolthouse Jonathan T, Lane Brian R, Anema John G, Kahnoski Richard J, Tan Patrick, Teh Bin Tean, Rozen Steven G

Abstract excerpt

BACKGROUND: Testicular germ cell tumors are the most common cancer diagnosed in young men, and seminomas are the most common type of these cancers. There have been no exome-wide examinations of genes mutated in seminomas or of overall rates of nonsilent somatic mutations in these tumors. OBJECTIVE: The objective was to analyze somatic mutations in seminomas to determine which genes are affected and to determine...

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Source

Identifiers

PMID: 25597018
DOI: 10.1016/j.eururo.2014.12.040

Genes

KIT
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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