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Article

Associations of HSD11B1 polymorphisms with tacrolimus concentrations in Chinese renal transplant recipients with prednisone combined therapy.

Drug metabolism and disposition: the biological fate of chemicals - 1 Apr 2015

Liu Xiaoman, Li Jiali, Fu Qian, Liu Shu, Zhang Yu, Wang Xueding, Wang Hongyang, Li Jun, Zhu Chen, Wang Changxi, Huang Min

Abstract excerpt

Tacrolimus requires close therapeutic drug monitoring because of its narrow therapeutic index and marked interindividual pharmacokinetic variation. In this study, we investigated the associations of polymorphisms in the gene encoding 11β-hydroxysteroid dehydrogenase type 1 (HSD11B1) with tacrolim...

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Source

Identifiers

PMID: 25587129
DOI: 10.1124/dmd.114.062117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25587129-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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