Article
Prednisolone and Prednisone Pharmacokinetics in Pediatric Renal Transplant Recipients-A Prospective Study.
Therapeutic drug monitoring - 1 Oct 2017
Skauby Ragnhild Heier, Bjerre Anna, Sæves Ingjerd, Vethe Nils Tore, Bremer Sara, Svarstad Anja, Bergan Stein
Abstract excerpt
BACKGROUND: Prednisolone is a standard component of immunosuppressive protocols in renal transplantation (Tx) and despite standardized treatment regimens, adverse side effects are still frequent. The aim of this study was to characterize the pharmacokinetics of prednisolone and prednisone in pediatric renal transplant recipients in the first 52 weeks post Tx, to describe the relationship between prednisolone and...
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