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[Associations of SLCO1B1 polymorphisms with tacrolimus concentrations in Chinese renal transplant recipients].

Yao xue xue bao = Acta pharmaceutica Sinica - 1 Aug 2016

Liu Shu, Chen Rong-xin, Li Jun, Liu Xiao-man, Huang Hong-bing, Fu Qian, Wang Chang-xi, Huang Min, Li Jia-li

Abstract excerpt

The study aims to investigate the associations of SLCO1B1 polymorphisms with tacrolimus concentrations in Chinese renal transplant recipients. Blood samples and clinical data were collected from 89 renal transplant recipients with tacrolimus treatment. CYP3A5*3 genotypes were detected by PCR-RFLP method and SLCO1B1(rs2306283, rs4149032) genotypes were detected by Agena Bioscience Mass ARRAY® system. Trough...

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PMID: 29897725

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