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Article

Emotional disorders in adult mice heterozygous for the transcription factor Phox2b.

Physiology & behavior - 15 Mar 2015

Bollen Bieke, Ramanantsoa Nelina, Naert Arne, Matrot Boris, Van den Bergh Omer, D'Hooge Rudi, Gallego Jorge

Abstract excerpt

Phox2b is an essential transcription factor for the development of the autonomic nervous system. Mice carrying one invalidated Phox2b allele (Phox2b(+/-)) show mild autonomic disorders including sleep apneas, and impairments in chemosensitivity and thermoregulation that recover within 10days of postnatal age. Because Phox2b is not expressed above the pons nor in the cerebellum, this mutation is not expected to...

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Source

Identifiers

PMID: 25582512
DOI: 10.1016/j.physbeh.2015.01.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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