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Article

PHOX2B in respiratory control: lessons from congenital central hypoventilation syndrome and its mouse models.

Respiratory physiology & neurobiology - 31 Aug 2009

Amiel Jeanne, Dubreuil Véronique, Ramanantsoa Nélina, Fortin Gilles, Gallego Jorge, Brunet Jean-François, Goridis Christo

Abstract excerpt

Phox2b is a master regulator of visceral reflex circuits. Its role in the control of respiration has been highlighted by the identification of heterozygous PHOX2B mutations as the cause of Central Congenital Hypoventilation Syndrome (CCHS), a rare disease defined by the lack of CO(2) responsivene...

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Identifiers

PMID: 19712905
DOI: 10.1016/j.resp.2009.03.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19712905-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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