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Transcription factor mesenchyme homeobox protein 2 (MEOX2) modulates nociceptor function

13 Jan 2022

Abstract excerpt

Mesenchyme homeobox protein 2 (MEOX2) is a transcription factor involved in mesoderm differentiation, including development of bones, muscles, vasculature and dermatomes. We have previously identified dysregulation of MEOX2 in fibroblasts from Congenital Insensitivity to Pain patients, and confirmed that btn , the Drosophila homologue of MEOX2 , plays a role in nocifensive responses to noxious heat stimuli. To...

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PMID: 35029322
DOI: 10.1111/febs.16347

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