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Expression of Phox2b by Brainstem Neurons Involved in Chemosensory Integration in the Adult Rat

4 Oct 2006

Abstract excerpt

Central congenital hypoventilation syndrome is caused by mutations of the gene that encodes the transcription factor Phox2b. The syndrome is characterized by a severe form of sleep apnea attributed to greatly compromised central and peripheral chemoreflexes. In this study, we analyze whether Phox2b expression in the brainstem respiratory network is preferentially associated with neurons involved in chemosensory...

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PMID: 17021186
DOI: 10.1523/jneurosci.2917-06.2006

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Expression of Phox2b by Brainstem Neurons Involved in Chemosensory Integration in the Adult RatPMID 17021186Read ↗

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