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<i>Phox2b</i>controls the development of peripheral chemoreceptors and afferent visceral pathways

25 Nov 2003

Abstract excerpt

We report that the afferent relays of visceral (cardiovascular, digestive and respiratory) reflexes, differentiate under the control of the paired-like homeobox gene Phox2b: the neural crest-derived carotid body, a chemosensor organ, degenerates in homozygous mutants, as do the three epibranchial placode-derived visceral sensory ganglia (geniculate, petrosal and nodose), while their central target, the nucleus of...

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PMID: 14627719
DOI: 10.1242/dev.00866

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