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Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the Dengue disease severity

13 Oct 2023

Abstract excerpt

The pathological outcome of dengue disease results from complex interactions between dengue virus (DENV) and host genetics and immune response. Complement receptor types 1 and 2 (CR1 and CR2) mediate complement activation through the alternative pathway. This study investigated the possible association of genetic polymorphisms and plasma levels of CR1 and CR2 with dengue disease. A total of 267 dengue patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37833411
DOI: 10.1038/s41598-023-44512-w

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