Article
Study of common functional genetic polymorphisms of FCGR2A, 3A and 3B genes and the risk for cryptococcosis in HIV-uninfected patients.
Medical mycology - 1 Sept 2007
Meletiadis Joseph, Walsh Thomas J, Choi Eun Hwa, Pappas Peter G, Ennis David, Douglas Jeffrey, Pankey George A, Larsen Robert A, Hamill Richard J, Chanock Stephen
Abstract excerpt
A pilot candidate gene association study was conducted to investigate the role of three common functional genetic polymorphisms of the low-affinity Fc gamma receptors, FCGR2A (131H/R), FCGR3A (158F/V) and FCGR3B (NA1/NA2) in Cryptococcus neoformans infections in individuals not infected with HIV. The FCGR2A 131RR and FCGR3A 158VV genotypes were over-represented [OR: 1.67 (1.05-2.63) and 2.04 (1.06-4.00),...
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