Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human complement receptor type 1 (CR1) protein levels and genetic variants in chronic Chagas Disease.

Scientific reports - 11 Jan 2018

Sandri Thaisa Lucas, Lidani Kárita Cláudia Freitas, Andrade Fabiana Antunes, Meyer Christian G, Kremsner Peter G, de Messias-Reason Iara J, Velavan Thirumalaisamy P

Abstract excerpt

Complement is an essential element in both innate and acquired immunity contributing to the immunopathogenesis of many disorders, including Chagas Disease (CD). Human complement receptor 1 (CR1) plays a role in the clearance of complement opsonized molecules and may facilitate the entry of pathogens into host cells. Distinct CR1 exon 29 variants have been found associated with CR1 expression levels, increased...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chagas Disease

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Share to Receptors, Complement 3b

Source

Open in PubMed Open full text

Identifiers

PMID: 29323238
DOI: 10.1038/s41598-017-18937-z
PMCID: PMC5765048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human complement receptor type 1 (CR1) protein levels and genetic variants in chronic Chagas Disease.PMID 29323238Read ↗

Geographical distribution of complement receptor type 1 variants and their associated disease risk.Semantic proximity Read ↗

The structure, genetic polymorphisms, expression and biological functions of complement receptor type 1 (CR1/CD35).Semantic proximity Read ↗

Targeted genotyping of COVID-19 patients reveals a signature of complement C3 and factor B coding SNPs associated with severe infection.Semantic proximity Read ↗

Common and rare variants in complement genes as biomarkers of COVID-19 infection and severity. A lesson to learn for emerging pathogens.Semantic proximity Read ↗

Methodological Appraisal of Literature Concerning the Analysis of Genetic Variants or Protein Levels of Complement Components on Susceptibility to Infection by Trypanosomatids: A Systematic Review.Semantic proximity Read ↗

CR1 levels and gene polymorphisms exhibit differential association with falciparum malaria in regions of varying disease endemicity.Semantic proximity Read ↗

Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy.Semantic proximity Read ↗

Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the Dengue disease severitySemantic proximity Read ↗

Identification of complement receptor one (CR1) polymorphisms in West AfricaSemantic proximity Read ↗

Germline rare variants of lectin pathway genes predispose to asymptomatic SARS-CoV-2 infection in elderly individualsSemantic proximity Read ↗

Complement Receptor 1 (CR1, CD35) Polymorphisms and Soluble CR1: A Proposed Anti-inflammatory Role to Quench the Fire of "Fogo Selvagem" Pemphigus Foliaceus.Semantic proximity Read ↗

Structural and functional correlation of the human complement receptor type 1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.