Article
A FcɣRIIa polymorphism has a HLA-B57 and HLA-B27 independent effect on HIV disease outcome.
Genes and immunity - 1 Aug 2020
Carapito Raphael, Mayr Luzia, Molitor Anne, Verniquet Martin, Schmidt Sylvie, Tahar Ouria, Partisani Marialuisa, Rey David, Lambotte Olivier, Bahram Seiamak, Moog Christiane
Abstract excerpt
Fcɣ receptors (FcɣRs) are key immune regulatory receptors that connect antibody-mediated immune responses to cellular effector functions. They are involved in the control of various immune functions including responses to infections. Genetic polymorphisms of FcɣRs coding genes (FCGR) have been associated with the regulation of HIV infection and progression. In this study, we analyzed the potential impact of five...
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