Article
Biosynthesis of cell envelope-associated phenolic glycolipids in Mycobacterium marinum.
Journal of bacteriology - 1 Mar 2015
Vergnolle Olivia, Chavadi Sivagami Sundaram, Edupuganti Uthamaphani R, Mohandas Poornima, Chan Catherine, Zeng Julie, Kopylov Mykhailo, Angelo Nicholas G, Warren J David, Soll Clifford E, Quadri Luis E N
Abstract excerpt
Phenolic glycolipids (PGLs) are polyketide synthase-derived glycolipids unique to pathogenic mycobacteria. PGLs are found in several clinically relevant species, including various Mycobacterium tuberculosis strains, Mycobacterium leprae, and several nontuberculous mycobacterial pathogens, such as M. marinum. Multiple lines of investigation implicate PGLs in virulence, thus underscoring the relevance of a deep...
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