Article

Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE

2024-09-18

Abstract excerpt

Tuberculosis (TB), exceeded in mortality only by COVID-19 among global infectious diseases, is caused by Mycobacterium tuberculosis (Mtb). The pathogenicity of Mtb is largely attributed to its complex cell envelope, which includes a class of glycolipids called phosphatidyl-myo-inositol mannosides (PIMs), found uniquely in mycobacteria and its related corynebacterineae. These glycolipids maintain the integrity of t...

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Literature Corpus work: c3e4dbea-5fe2-5b03-8dad-53079ae261f9
DOI: 10.1101/2024.09.17.613550

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