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Both phthiocerol dimycocerosates and phenolic glycolipids are required for virulence of Mycobacterium marinum.

Infection and immunity - 1 Apr 2012

Yu Jia, Tran Vanessa, Li Ming, Huang Xinghua, Niu Chen, Wang Decheng, Zhu Jianghua, Wang Jianping, Gao Qian, Liu Jun

Abstract excerpt

Phthiocerol dimycocerosates (PDIMs) and structurally related phenolic glycolipids (PGLs) are complex cell wall lipids unique to pathogenic mycobacteria. While these lipids have been extensively studied in recent years, there are conflicting reports on some aspects of their biosynthesis and on the role of PDIMs and especially PGLs in virulence of Mycobacterium tuberculosis. This has been complicated by the natural...

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Bacterial Proteins
Cell Wall
Glycolipids
Lipids
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mycobacterium Infections, Nontuberculous

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PMID: 22290144
DOI: 10.1128/IAI.06370-11
PMCID: PMC3318414

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