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Article

The mycobacterial acyltransferase PapA5 is required for biosynthesis of cell wall-associated phenolic glycolipids.

Microbiology (Reading, England) - 1 May 2012

Chavadi Sivagami Sundaram, Onwueme Kenolisa C, Edupuganti Uthamaphani R, Jerome Jeff, Chatterjee Delphi, Soll Clifford E, Quadri Luis E N

Abstract excerpt

Phenolic glycolipids (PGLs) are non-covalently bound components of the outer membrane of many clinically relevant mycobacterial pathogens, and play important roles in pathogen biology. We report a mutational analysis that conclusively demonstrates that the conserved acyltransferase-encoding gene papA5 is essential for PGL production. In addition, we provide an in vitro acyltransferase activity analysis that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22361940
DOI: 10.1099/mic.0.057869-0
PMCID: PMC3542824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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