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Article

Kizuna is a novel mitotic substrate for CDC25B phosphatase.

Cell cycle (Georgetown, Tex.) - 1 Jan 2014

Thomas Yann, Peter Marion, Mechali Francisca, Blanchard Jean-Marie, Coux Olivier, Baldin Véronique

Abstract excerpt

CDC25 dual-specificity phosphatases play a central role in cell cycle control through the activation of Cyclin-Dependent Kinases (CDKs). Expression during mitosis of a stabilized CDC25B mutant (CDC25B-DDA), which cannot interact with the F-box protein βTrCP for proteasome-dependent degradation, causes mitotic defects and chromosome segregation errors in mammalian cells. We found, using the same CDC25B mutant,...

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Identifiers

PMID: 25558830
DOI: 10.4161/15384101.2014.972882
PMCID: PMC4615109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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