Article
Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Feb 1997
Wang Y, Burke D J
Abstract excerpt
Saccharomyces cerevisiae, like most eucaryotic cells, can prevent the onset of anaphase until chromosomes are properly aligned on the mitotic spindle. We determined that Cdc55p (regulatory B subunit of protein phosphatase 2A [PP2A]) is required for the kinetochore/spindle checkpoint regulatory pa...
Topics
- Cell Cycle Proteins
- DNA Damage
- DNA, Fungal
- Fungal Proteins
- Gamma Rays
- Genetic Complementation Test
- Hydroxyurea
- Kinetochores
- Microtubules
- Mitosis
- Mutation
- Nocodazole
- Nuclear Proteins
- Nucleic Acid Synthesis Inhibitors
- Phosphoprotein Phosphatases
- Phosphorylation
- Protamine Kinase
- Protein Phosphatase 2