Article
Genetic and functional diversity of propagating cells in glioblastoma.
Stem cell reports - 13 Jan 2015
Piccirillo Sara G M, Colman Sue, Potter Nicola E, van Delft Frederik W, Lillis Suzanne, Carnicer Maria-Jose, Kearney Lyndal, Watts Colin, Greaves Mel
Abstract excerpt
Glioblastoma (GBM) is a lethal malignancy whose clinical intransigence has been linked to extensive intraclonal genetic and phenotypic diversity and the common emergence of therapeutic resistance. This interpretation embodies the implicit assumption that cancer stem cells or tumor-propagating cel...
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