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The Evidence of Glioblastoma Heterogeneity

27 Jan 2015

Abstract excerpt

Cancers are composed of heterogeneous combinations of cells that exhibit distinct phenotypic characteristics and proliferative potentials. Because most cancers have a clonal origin, cancer stem cells (CSCs) must generate phenotypically diverse progenies including mature CSCs that can self-renew indefinitely and differentiated cancer cells that possess limited proliferative potential. However, no convincing...

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PMID: 25623281
DOI: 10.1038/srep07979

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