Article
Pattern of variation in the mono- and dinucleotide repeat microsatellites associated with lynch syndrome in an Indian population.
Oncology research and treatment - 1 Jan 2014
Vaniawala Salil, Acharya Arpan, Parekh Harsh, Bapat Anuja, Mukhopadhyaya Pratap N
Abstract excerpt
BACKGROUND: Microsatellite instability (MSI) is associated with Lynch syndrome and hence is a surrogate marker for defective mismatch repair genes. The aim of this study was to investigate the degree of instability associated with each of the 5 microsatellite (MS) loci recommended by the National Cancer Institute (NCI), USA within an Indian population of mixed ethnicity and suffering from Lynch syndrome. METHODS:...
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