Article
Assessment of microsatellite instability in colorectal carcinoma at an Indian center.
International journal of colorectal disease - 1 Jul 2007
Pandey Vijay, Prabhu Jyothi S, Payal K, Rajan Veena, Deepak C, Barde Shubhada, Jagannath P, Borges Anita, Sridhar T S
Abstract excerpt
AIM: The purpose of the present study was to evaluate the frequency of microsatellite instability (MSI) in colorectal cancers in an Indian cohort. MATERIALS AND METHODS: Paraffin embedded tissue samples of colorectal cancers from 46 patients were assessed for mismatch repair protein expression (hMLH1 and hMSH2) by immunohistochemistry. Subsequently, MSI analysis was done after PCR amplification of five Bethesda...
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