Article
Insertion/deletion polymorphisms are convenient and reliable markers to assess chromosomal instability in human tumors.
The International journal of biological markers - 8 Oct 2012
Marchio Agnès, Akil Abdellah, Terris Benoît, Dejean Anne, Pineau Pascal
Abstract excerpt
Chromosomal instability (CIN) is frequently associated with a poor outcome in human carcinomas. The genomes of the main human malignancies are well defined as hundreds of tumors have been characterized by arrays. Targeting the appropriate chromosomes with set of markers appears as a realistic approach for CIN assessment. We decided to test the reliability of different insertion/deletion (InDel) polymorphisms to...
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