Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Utility of the quasi‐monomorphic variation range in unresectable metastatic colorectal cancer patients

24 Aug 2018

Abstract excerpt

Microsatellite Instability (MSI) status is an established predictive biomarker for the treatment of the anti-programmed death 1 (PD-1) antibody. The current approach to determine the MSI status in tumours requires matched normal DNA. Some mononucleotide microsatellite markers are known to have few variant alleles in both Caucasians and Asians. Therefore, the length of these microsatellite makers is almost...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Colorectal Cancer Treatments and Studies
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30142704
DOI: 10.1111/cas.13774

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Utility of the quasi‐monomorphic variation range in unresectable metastatic colorectal cancer patientsPMID 30142704Read ↗

MSI‐L/EMAST is a predictive biomarker for metastasis in colorectal cancer patientsSemantic proximity Read ↗

Detection of Microsatellite Instability: State of the Art and Future Applications in Circulating Tumour DNA (ctDNA)Semantic proximity Read ↗

Accuracy of four mononucleotide-repeat markers for the identification of DNA mismatch-repair deficiency in solid tumors.Semantic proximity Read ↗

An optimized pentaplex PCR for detecting DNA mismatch repair-deficient colorectal cancers.Semantic proximity Read ↗

Detection of microsatellite instability in colorectal cancer using an alternative multiplex assay of quasi-monomorphic mononucleotide markers.Semantic proximity Read ↗

Applicability of Next Generation Sequencing Technology in Microsatellite Instability TestingSemantic proximity Read ↗

Microsatellite instability test using peptide nucleic acid probe-mediated melting point analysis: a comparison studySemantic proximity Read ↗

Microsatellite Status Detection of Colorectal Cancer: Evaluation of Inconsistency between PCR and IHCSemantic proximity Read ↗

Quasimonomorphic mononucleotide repeats for high-level microsatellite instability analysis.Semantic proximity Read ↗

Impact of Pre-Analytical Factors on MSI Test Accuracy in Mucinous Colorectal Adenocarcinoma: A Multi-Assay Concordance StudySemantic proximity Read ↗

Development of a fluorescent multiplex assay for detection of MSI-High tumors.Semantic proximity Read ↗

A novel panel of short mononucleotide repeats linked to informative polymorphisms enabling effective high volume low cost discrimination between mismatch repair deficient and proficient tumoursSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.