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Article

Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Jan 2006

Buhard Olivier, Cattaneo Francesca, Wong Yick Fu, Yim So Fan, Friedman Eitan, Flejou Jean-François, Duval Alex, Hamelin Richard

Abstract excerpt

PURPOSE: Human gastrointestinal tumors with inactivated DNA mismatch repair system (microsatellite instability [MSI] tumors) have distinct molecular and clinicopathologic profiles, and are associated with favorable prognosis. There is evidence suggesting that colorectal cancer patients with MSI tumors respond differently to adjuvant chemotherapy as compared with patients with non-MSI tumors. Finally,...

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Identifiers

PMID: 16330668
DOI: 10.1200/JCO.2005.02.7227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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