Article
Profiling of exome mutations associated with progression of HBV-related hepatocellular carcinoma.
PloS one - 1 Jan 2014
Woo Hyun Goo, Kim Soon Sun, Cho Hyunwoo, Kwon So Mee, Cho Hyo Jung, Ahn Seun Joo, Park Eun Sung, Lee Ju-Seog, Cho Sung Won, Cheong Jae Youn
Abstract excerpt
Recent advances in sequencing technology have allowed us to profile genome-wide mutations of various cancer types, revealing huge heterogeneity of cancer genome variations. However, its heterogeneous landscape of somatic mutations according to liver cancer progression is not fully understood. Here, we profiled the mutations and gene expressions of early and advanced hepatocellular carcinoma (HCC) related with...
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