Article
Integrative analysis of highly mutated genes in hepatitis B virus-related hepatic carcinoma.
Cancer medicine - 1 Apr 2020
Kong Fanyun, Kong Delong, Yang Xiaoying, Yuan Dongchen, Zhang Ning, Hua Xuan, You Hongjuan, Zheng Kuiyang, Tang Renxian
Abstract excerpt
Gene mutation is responsible for the development of hepatocellular carcinoma (HCC) with hepatitis B virus (HBV) infection; however, the characteristics and associated biological functions of highly mutated genes, in which the mutation frequencies are at least 5% in HCC patients with HBV infection...
Topics
- Biomarkers, Tumor
- Carcinoma, Hepatocellular
- Female
- Follow-Up Studies
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- Gene Regulatory Networks
- Hepatitis B
- Hepatitis B virus
- Humans
- Liver Neoplasms
- Male
- Middle Aged
- Mutation
- Prognosis