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The Bacterial Type <scp>III</scp> Secretion System as a Target for Developing New Antibiotics

17 Dec 2014

Abstract excerpt

Antibiotic resistance in pathogens requires new targets for developing novel antibacterials. The bacterial type III secretion system (T3SS) is an attractive target for developing antibacterials as it is essential in the pathogenesis of many Gram-negative bacteria. The T3SS consists of structural proteins, effectors, and chaperones. Over 20 different structural proteins assemble into a complex nanoinjector that...

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PMID: 25521643
DOI: 10.1111/cbdd.12422

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