Article
Identification of the Targets of Type III Secretion System Inhibitors.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Condry Danielle L Jessen, Nilles Matthew L
Abstract excerpt
A type III secretion system (T3SS) Inhibitor can be utilized for study in the research lab but also progressed into drug development. Since many pathogenic Gram-negative bacteria utilize this highly conserved system as a virulence factor, the prospect of the T3SS as a drug target is promising. To effectively move a T3SS inhibitor into the route of either research or pharmaceuticals an understanding of the target...
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