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Article

Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa.

PloS one - 1 Jan 2016

Gerits Evelien, Blommaert Eline, Lippell Anna, O'Neill Alex J, Weytjens Bram, De Maeyer Dries, Fierro Ana Carolina, Marchal Kathleen, Marchand Arnaud, Chaltin Patrick, Spincemaille Pieter, De Brucker Katrijn, Thevissen Karin, Cammue Bruno P A, Swings Toon, Liebens Veerle, Fauvart Maarten, Verstraeten Natalie, Michiels Jan

Abstract excerpt

Nosocomial and community-acquired infections caused by multidrug resistant bacteria represent a major human health problem. Thus, there is an urgent need for the development of antibiotics with new modes of action. In this study, we investigated the antibacterial characteristics and mode of action of a new antimicrobial compound, SPI031 (N-alkylated 3, 6-dihalogenocarbazol...

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Identifiers

PMID: 27167126
DOI: 10.1371/journal.pone.0155139
PMCID: PMC4864301

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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