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Article

The salicylidene acylhydrazide INP0341 attenuates Pseudomonas aeruginosa virulence in vitro and in vivo.

The Journal of antibiotics - 1 Aug 2017

Uusitalo Pia, Hägglund Ulrik, Rhöös Elin, Scherman Norberg Henrik, Elofsson Mikael, Sundin Charlotta

Abstract excerpt

Pseudomonas aeruginosa is an opportunistic pathogen that can be very hard to treat because of high resistance to different antibiotics and alternative treatment regimens are greatly needed. An alternative or a complement to traditional antibiotic is to inhibit virulence of the bacteria. The salicylidene acylhydrazide, INP0341, belongs to a class of compounds that has previously been shown to inhibit virulence in...

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Identifiers

PMID: 28588224
DOI: 10.1038/ja.2017.64

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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