Association of the LRRK2 genetic polymorphisms with leprosy in Han Chinese from Southwest China.

doi:10.1038/gene.2014.72

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Association of the LRRK2 genetic polymorphisms with leprosy in Han Chinese from Southwest China.

Genes and immunity - 1 Mar 2015

Wang D, Xu L, Lv L, Su L-Y, Fan Y, Zhang D-F, Bi R, Yu D, Zhang W, Li X-A, Li Y-Y, Yao Y-G

Abstract excerpt

Leprosy is a chronic infectious and neurological disease that is caused by infection of Mycobacterium leprae (M. leprae). A recent genome-wide association study indicated a suggestive association of LRRK2 genetic variant rs1873613 with leprosy in Chinese population. To validate this association and further identify potential causal variants of LRRK2 with leprosy, we genotyped 13 LRRK2 variants in 548 leprosy...

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PMID: 25521227
DOI: 10.1038/gene.2014.72

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