Article
Genome-Wide Analysis of Protein-Coding Variants in Leprosy.
The Journal of investigative dermatology - 1 Dec 2017
Liu Hong, Wang Zhenzhen, Li Yi, Yu Gongqi, Fu Xi'an, Wang Chuan, Liu Wenting, Yu Yongxiang, Bao Fangfang, Irwanto Astrid, Liu Jian, Chu Tongsheng, Andiappan Anand Kumar, Maurer-Stroh Sebastian, Limviphuvadh Vachiranee, Wang Honglei, Mi Zihao, Sun Yonghu, Sun Lele, Wang Ling, Wang Chaolong, You Jiabao, Li Jinghui, Foo Jia Nee, Liany Herty, Meah Wee Yang, Niu Guiye, Yue Zhenhua, Zhao Qing, Wang Na, Yu Meiwen, Yu Wenjun, Cheng Xiujun, Khor Chiea Chuen, Sim Kar Seng, Aung Tin, Wang Ningli, Wang Deyun, Shi Li, Ning Yong, Zheng Zhongyi, Yang Rongde, Li Jinlan, Yang Jun, Yan Liangbin, Shen Jianping, Zhang Guocheng, Chen Shumin, Liu Jianjun, Zhang Furen
Abstract excerpt
Although genome-wide association studies have greatly advanced our understanding of the contribution of common noncoding variants to leprosy susceptibility, protein-coding variants have not been systematically investigated. We carried out a three-stage genome-wide association study of protein-coding variants in Han Chinese, of whom were 7,048 leprosy patients and 14,398 were healthy control subjects. Seven coding...
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