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Article

JEPEG: a summary statistics based tool for gene-level joint testing of functional variants.

Bioinformatics (Oxford, England) - 15 Apr 2015

Lee Donghyung, Williamson Vernell S, Bigdeli T Bernard, Riley Brien P, Fanous Ayman H, Vladimirov Vladimir I, Bacanu Silviu-Alin

Abstract excerpt

MOTIVATION: Gene expression is influenced by variants commonly known as expression quantitative trait loci (eQTL). On the basis of this fact, researchers proposed to use eQTL/functional information univariately for prioritizing single nucleotide polymorphisms (SNPs) signals from genome-wide association studies (GWAS). However, most genes are influenced by multiple eQTLs which, thus, jointly affect any downstream...

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Identifiers

PMID: 25505091
DOI: 10.1093/bioinformatics/btu816
PMCID: PMC4393522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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