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Article

GenoWAP: GWAS signal prioritization through integrated analysis of genomic functional annotation.

Bioinformatics (Oxford, England) - 15 Feb 2016

Lu Qiongshi, Yao Xinwei, Hu Yiming, Zhao Hongyu

Abstract excerpt

MOTIVATION: Genome-wide association study (GWAS) has been a great success in the past decade. However, significant challenges still remain in both identifying new risk loci and interpreting results. Bonferroni-corrected significance level is known to be conservative, leading to insufficient statistical power when the effect size is moderate at risk locus. Complex structure of linkage disequilibrium also makes it...

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PMID: 26504140
DOI: 10.1093/bioinformatics/btv610
PMCID: PMC5963360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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