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Islet inflammation in human type 1 diabetes mellitus

1 Nov 2014

Abstract excerpt

Type 1 diabetes mellitus (T1DM) is caused by the selective deletion of pancreatic β-cells in response to an assault mounted within the pancreas by infiltrating immune cells. However, this apparently clear and focussed annunciation conceals a stark reality in which the cellular and molecular events leading to β-cell loss remain poorly understood in humans. This reflects the difficulty of studying these processes...

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PMID: 25504835
DOI: 10.1002/iub.1330

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