Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cracking the type 1 diabetes code: Genes, microbes, immunity, and the early life environment.

Immunological reviews - 1 Aug 2024

Yau Christopher, Danska Jayne S

Abstract excerpt

Type 1 diabetes (T1D) results from a complex interplay of genetic predisposition, immunological dysregulation, and environmental triggers, that culminate in the destruction of insulin-secreting pancreatic β cells. This review provides a comprehensive examination of the multiple factors underpinning T1D pathogenesis, to elucidate key mechanisms and potential therapeutic targets. Beginning with an exploration of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Autoimmunity
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Gastrointestinal Microbiome

Share to Gene-Environment Interaction

Share to HLA Antigens

Share to Insulin-Secreting Cells

Source

Identifiers

PMID: 39166298
DOI: 10.1111/imr.13362

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cracking the type 1 diabetes code: Genes, microbes, immunity, and the early life environment.PMID 39166298Read ↗

Type 1 Diabetes: A Guide to Autoimmune Mechanisms for Clinicians.Semantic proximity Read ↗

Pathogenesis of Type 1 Diabetes: Established Facts and New Insights.Semantic proximity Read ↗

Type 1 diabetes: etiology, immunology, and therapeutic strategies.Semantic proximity Read ↗

The long and winding road to understanding and conquering type 1 diabetes.Semantic proximity Read ↗

Type 1 diabetes: lessons for other autoimmune diseases?Semantic proximity Read ↗

The Multifactorial Progression from the Islet Autoimmunity to Type 1 Diabetes in Children.Semantic proximity Read ↗

The perfect storm: unraveling the interplay of genetic predisposition and viral triggers in type 1 diabetes pathogenesis.Semantic proximity Read ↗

The multiple origins of Type 1 diabetes.Semantic proximity Read ↗

The Chicken or the Egg Dilemma: Understanding the Interplay between the Immune System and the β Cell in Type 1 Diabetes.Semantic proximity Read ↗

New Insights and Biomarkers for Type 1 Diabetes: Review for Scandinavian Journal of Immunology.Semantic proximity Read ↗

Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals.Semantic proximity Read ↗

Gene-environment interaction in the pathophysiology of type 1 diabetesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.