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Article

The multiple origins of Type 1 diabetes.

Diabetic medicine : a journal of the British Diabetic Association - 1 Feb 2013

Pugliese A

Abstract excerpt

It is widely accepted that Type 1 diabetes is a complex disease. Genetic predisposition and environmental factors favour the triggering of autoimmune responses against pancreatic β-cells, eventually leading to β-cell destruction. Over 40 susceptibility loci have been identified, many now mapped to known genes, largely supporting a dominant role for an immune-mediated pathogenesis. This role is also supported by...

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Source

Identifiers

PMID: 23181718
DOI: 10.1111/dme.12081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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