Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pathogenesis of Type 1 Diabetes: Established Facts and New Insights.

Genes - 16 Apr 2022

Zajec Ana, Trebušak Podkrajšek Katarina, Tesovnik Tine, Šket Robert, Čugalj Kern Barbara, Jenko Bizjan Barbara, Šmigoc Schweiger Darja, Battelino Tadej, Kovač Jernej

Abstract excerpt

Type 1 diabetes (T1D) is an autoimmune disease characterized by the T-cell-mediated destruction of insulin-producing β-cells in pancreatic islets. It generally occurs in genetically susceptible individuals, and genetics plays a major role in the development of islet autoimmunity. Furthermore, these processes are heterogeneous among individuals; hence, different endotypes have been proposed. In this review, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmunity
Share to Diabetes and associated disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Management and Research

Share to Diabetes Mellitus, Type 1

Share to Epigenomics

Share to Genetic Predisposition to Disease

Share to Islets of Langerhans

Share to Pancreatic function and diabetes

Source

Open in PubMed Open full text

Identifiers

PMID: 35456512
DOI: 10.3390/genes13040706
PMCID: PMC9032728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pathogenesis of Type 1 Diabetes: Established Facts and New Insights.PMID 35456512Read ↗

Type 1 diabetes: etiology, immunology, and therapeutic strategies.Semantic proximity Read ↗

The multiple origins of Type 1 diabetes.Semantic proximity Read ↗

Type 1 Diabetes: A Guide to Autoimmune Mechanisms for Clinicians.Semantic proximity Read ↗

The long and winding road to understanding and conquering type 1 diabetes.Semantic proximity Read ↗

Cracking the type 1 diabetes code: Genes, microbes, immunity, and the early life environment.Semantic proximity Read ↗

Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals.Semantic proximity Read ↗

New Insights and Biomarkers for Type 1 Diabetes: Review for Scandinavian Journal of Immunology.Semantic proximity Read ↗

Beyond Genetics: What Causes Type 1 Diabetes.Semantic proximity Read ↗

The perfect storm: unraveling the interplay of genetic predisposition and viral triggers in type 1 diabetes pathogenesis.Semantic proximity Read ↗

Environmental trigger(s) of type 1 diabetes: why so difficult to identify?Semantic proximity Read ↗

Type 1 diabetes: current concepts in epidemiology, pathophysiology, clinical care, and research.Semantic proximity Read ↗

The Multifactorial Progression from the Islet Autoimmunity to Type 1 Diabetes in Children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.